« ...The basic cause of acne is still unknown. It seems to be a multifactorial disease in which interaction of several factors play an important part in the pathogenesis. The primary event may be (a) obstruction of the sebaceous duct due to alteration in the pattern of keratinization within the follicle, (b) abnormal sebum production with excess quantities or altered composition or (c) increased bacterial colonization (proprionibacterium acnes and staphylococcus epidermi¬dis of pilosebaceous follicles which furnish the lipases responsible for hydrolysis of sebum triglycerides into free fatty acids. All three mechanisms may be involved. Obstruction of duct leads to forma¬tion of a comedone, the initial lesion of acne. A comedone can be located either in a closed follicle as a 'white head' consisting of lipid and keratin, or in an open follicle as 'black head' consisting of keratin and lipid with melanin deposition. The continual accumula¬tion of keratin and lipid may lead to rupture of the follicular wall and release of its contents into the surrounding dermis provoking an inflammatory tissue reaction....
...Firstly, there are some facts that all people need to do so that they can get, as well as, keep, clear vibrant skin. To flush and rid your body of impurities an excellent way would be for to drink plenty of water each day (minimum of half a gallon) because problems with the kidneys and liver can cause breakouts. Water can also provide dry skin with the moisture that it needs, and can also furnish oily skin with just the right amount of moisture balance....»
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acne-types.blogspot.com «...There are a number of causes of acne. Essentially it's about the wrong combination of bacteria and sebum, the oil produced by the sebaceous glands to moisturize the skin. Excess sebum can block the skin pores, the tiny holes all over the skin. When these become clogged the bacteria can take root and thrive, and dirt can get stuck, resulting in damaged pores, in the form of blackheads, pimples or whiteheads....»
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